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By Alton Meister

Evolution of Glutathione Metabolism (R. Fahey & A. Sundquist).

Covalent Inhibitors of the Gelation of Sickle cellphone Hemoglobin and Their results on functionality (J. Manning).

Structural foundation for Catalysis through Tryptophan Synthase (E. Miles).

constitution and Mechanism of F0F1-Type ATP Synthases and ATPases (H. Penefsky & R. Cross).

Novel features of the Biochemistry of the Molybdenum Cofactor (K. Rajagopalan).

Ovothiols: organic and Chemical views (B. Shapiro & P. Hopkins).

N?5-(1-Carboxyethyl)Ornithine and similar [N-Carboxyalkyl]-Amino Acids: constitution, Biosynthesis, and serve as (J. Thompson & S. Miller).

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Extra info for Advances in Enzymology and Related Areas of Molecular Biology, Volume 64

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64. , 97, 138-140 (1979). 65. , Proc. Narl. Acad. Sci. USA, 76, 5606-5610 (1979). 66. Meredith, M. J. and Reed, D. J.. J. Biol. , 257, 3747-3753 (1982). 67. Foyer, C. H. , Planra, 133, 21-25 (1976). 68. ,Phytochemistry, 21, 2771-2781 (1982). 69. Smith, I. ,Kendall, A. , Keys, A. , Turner, J. , and Lea, P. , 41, 11-17 (1985). 70. ,J. , 131, 123-131 (1987). 71. Cantatore, P. , Int. Rev. , 108, 149-208 (1987). 72. , Nature, 322, 572-574 (1986). 73. , Meng, B. , 5, 2043-2049 (1986). 74. GMith, 0. , Proc.

Vol. XIIIC,Boyer, P. , Academic Press, Orlando, 1976, pp. 89-173. Schirmer, R. , Krauth-Siegel. R. , and Schulz, G. , Wiley, New York, 1989, pp. 553-5%. , in Glutathione: Chemical, Biochemical, and Medical Aspects, Part 42 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 25. 26. 27. 28. 29. 30. 31. 32. 33. ROBERT C. FAHEY AND ALFRED R. , Wiley, New York, 1989, pp. 643-731. , and Boveris, A,, Physiol. , 59, 527-605 (1979). Mannervik. , in Enzymatic Basis ofDetoxication, Vol. 11, Jakoby, W.

Yes ? No? " GSH substantially converted to trypanothione (TSH); reductase specific for trypanothione. No? Yes ? Yes Yes Yes Yes ? Yes ? Yes Yes Yes Yes No' Yes Yes Yes Yes Yesb Eukaryotes No GSH-related thiols and no glutathione reductase found. y-Glutamylcysteine; reductase specific for yEC-disulfde. y-ECdependent. No' Yes No? No? Yes Yes Yes Yes Yes ? No No No No No No No No? Yes GSSG Thiol Formate Dehydroascorbate GSH Se-Dependent reductase transferase dehydrogenase reductase S-transferase peroxidase GSH GSH GSH GSH GSH GSH GSH" GSH TSH" No' RSH " Homoglutathioqe in some legumes.

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